Novel Discovery Reveals How Brain Protein OTULIN Controls Tau Expression and Could Transform Alzheimer’s Treatment
Groundbreaking research identifies unexpected role for deubiquitinase enzyme in regulating toxic tau protein accumulation
UTHSC In the Media
OTULIN enzyme found to control tau production in Alzheimer’s
New research has shown that the enzyme OTULIN regulates tau at the gene-expression level rather than through protein degradation.
Scientists uncover how brain enzyme OTULIN controls tau expression
Scientists have uncovered a surprising mechanism by which a brain enzyme called OTULIN controls the expression of tau, the protein that forms toxic tangles in Alzheimer’s disease.
Top Doctors 2025
Every year it is our privilege to ask the region’s physicians to put forward the peers they believe are stellar in their field.
University seeks state funding for $350M expansion
The University of Tennessee Health Science Center (UTHSC) has further discussed plans for its upcoming $350 million build.
Why toys matter in the exam room
Children often surprise us with the seriousness they bring to a clinic visit.
Ascension-Affiliated Doctors Dr. Phay Chothmounethinh and Dr. Helen K. Jones Advance Personalized Primary Care Through MDVIP
Two physician-led practices are making strong progress after recently launching their membership-based, preventive-care models in partnership with MDVIP.
Ascension-Affiliated Doctors Dr. Phay Chothmounethinh and Dr. Helen K. Jones Advance Personalized Primary Care Through MDVIP
Two physician-led practices are making strong progress after recently launching their membership-based, preventive-care models in partnership with MDVIP.