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Dynamically linking influenza virus infection kinetics, lung injury, inflammation, and disease severity

Written by Communications and Marketing

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Influenza viruses cause a significant amount of morbidity and mortality. Understanding host immune control efficacy and how different factors influence lung injury and disease severity are critical. We established and validated dynamical connections between viral loads, infected cells, CD8+ T cells, lung injury, inflammation, and disease severity using an integrative mathematical model-experiment exchange.

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