It is well known that patients with Alzheimer’s and other disorders, such as type 2 diabetes, develop amyloid, a substance composed of sticky protein fibers and sugar molecules that builds up in the brain or other organs in the body. Doctors do not know whether this material causes the diseases, or whether the diseases lead… Read More
Seriously ill patients who develop bacterial infections in the bloodstream require aggressive treatment with antibiotics. They also can develop kidney failure that requires hemodialysis.
In the United States, nearly 11 million caregivers provide 12.5 billion hours of care annually to those with Alzheimer’s disease, according to Linda Nichols, PhD, professor of Preventive Medicine and Internal Medicine at the University of Tennessee Health Science Center (UTHSC).
According to experts, breast cancer is a leading cause of cancer-related deaths in women worldwide. Among breast cancer patients, those diagnosed with triple-negative breast cancer (TNBC), an aggressive breast cancer subtype, have a lower survival rate, in part because there is a lack of effective targeted therapy. Chemotherapy is the only available systemic treatment for… Read More
Robert W. Williams, PhD, professor in the Departments of Anatomy and Neurobiology, and Pediatrics at the University of Tennessee Health Science Center (UTHSC) and director of the UT Center for Integrative and Translational Genomics, aims to make significant headway in studying the genetics of diet and aging, thanks to a new grant. The award, from… Read More
Tuberculosis (TB) is an infectious disease that is often contracted through an airborne bacterium known as Mycobacterium tuberculosis. It remains a leading public health problem worldwide, with an estimated 8 million new cases and 2 million deaths each year. Although most M. tuberculosis infections, known as pulmonary TB, are in the lungs, 5 to 10… Read More
As the population ages, Alzheimer’s disease is a major public health concern in the United States. An estimated 11 million to 16 million elderly will suffer from the disease by 2050. Aging is the most important risk factor for Alzheimer’s disease, but it is not clear to what extent the molecular changes that underlie normal… Read More
Gabor Tigyi, MD, PhD (back row, third from left) and his team. The threat of a nuclear accident, like the one at Fukushima, or the explosion of a nuclear device necessitates the development of radiation countermeasures that are safe and effective when applied 24 hours or later after a radiation injury. There are no such… Read More
