GTx, Inc. today announced that it has entered into an exclusive worldwide license agreement with the University of Tennessee Research Foundation (UTRF) to develop its proprietary selective androgen receptor degrader (SARD) technology which potentially can degrade and inhibit all forms of androgen receptor (AR), including those resistant to current therapies, to inhibit tumor growth in… Read More
Paraquat is a weed killer used extensively in agriculture in the United States and other parts of the world. It is suspected to increase risk for developing Parkinson’s disease. Byron Jones, PhD, and his research team are using newly awarded funds to investigate individual toxicity to the chemical on certain areas of the brain. Dr. Jones, a… Read More
George Huang, DDS, director and professor in the Department of Bioscience Research in the College of Dentistry at the University of Tennessee Health Science Center (UTHSC), is the recipient of the 2015 Distinguished Scientist Award in Pulp Biology given by the International Association for Dental Research (IADR). Dr. Huang was recognized during the opening ceremonies… Read More
John Bissler, MD, and his research team study a disease in children and adults called tuberous sclerosis complex (TSC), which predisposes patients to an unusual type of renal tumors. The team aims to use a newly developed model to study whether anti-hypertension drugs already approved for use in children will prevent tumors and the disease. Dr.… Read More
Rapid eye movement (REM) sleep, also known as dreaming sleep, is naturally regulated so that daily amounts are relatively consistent and losses are made up during the next period of sleep. This well-documented phenomenon is called REM sleep rebound. Subimal Datta, PhD, a professor in the University of Tennessee Health Science Center (UTHSC) Graduate School of… Read More
Glaucoma is a leading cause of irreversible blindness in the United States and globally. Currently, there is no cure for the disease, and once vision is lost, it cannot be regained. However, Robert. W. Williams, PhD, chair of the Department of Genetics, Genomics and Informatics at the University of Tennessee Health Science Center (UTHSC), has… Read More
Lawrence Pfeffer, PhD, Muirhead Professor of Pathology and director of the Center for Cancer Research at the University of Tennessee Health Science Center, is the principal author of a paper published in The Journal of Biological Chemistry that describes a little-known gene that could hold a key to future treatment of glioma, or brain cancer.… Read More
Small amounts of two heavy metals, lead and mercury, are naturally present in human blood. In adult transfusions these amounts are not significant enough to cause any concern. For extremely premature infants, however, the story is different. Frequent blood transfusions, which naturally contain lead and mercury, theoretically increase the risk of toxicity from these metals… Read More