Category: Research


GTx and the University of Tennessee Research Foundation Enter Into Exclusive License Agreement to Develop SARD Drug Candidate to Treat Castration-Resistant Prostate Cancer

|

GTx, Inc. today announced that it has entered into an exclusive worldwide license agreement with the University of Tennessee Research Foundation (UTRF) to develop its proprietary selective androgen receptor degrader (SARD) technology which potentially can degrade and inhibit all forms of androgen receptor (AR), including those resistant to current therapies, to inhibit tumor growth in… Read More


Professor Byron Jones Awarded $2.6 Million to Study Toxicity of the Herbicide Paraquat on the Brain

|

Paraquat is a weed killer used extensively in agriculture in the United States and other parts of the world. It is suspected to increase risk for developing Parkinson’s disease. Byron Jones, PhD, and his research team are using newly awarded funds to investigate individual toxicity to the chemical on certain areas of the brain. Dr. Jones, a… Read More


Professor George Huang, DDS, of UTHSC Receives 2015 IADR Distinguished Scientist Award in Pulp Biology

|

George Huang, DDS, director and professor in the Department of Bioscience Research in the College of Dentistry at the University of Tennessee Health Science Center (UTHSC), is the recipient of the 2015 Distinguished Scientist Award in Pulp Biology given by the International Association for Dental Research (IADR). Dr. Huang was recognized during the opening ceremonies… Read More


John Bissler, MD, Receives $637,501 Grant for Renal Tumor Research

|

John Bissler, MD, and his research team study a disease in children and adults called tuberous sclerosis complex (TSC), which predisposes patients to an unusual type of renal tumors. The team aims to use a newly developed model to study whether anti-hypertension drugs already approved for use in children will prevent tumors and the disease. Dr.… Read More


Professor Subimal Datta Receives $1.4 Million Grant to Study Molecular Processes of Rapid Eye Movement (REM) Sleep and Recovery

|

Rapid eye movement (REM) sleep, also known as dreaming sleep, is naturally regulated so that daily amounts are relatively consistent and losses are made up during the next period of sleep. This well-documented phenomenon is called REM sleep rebound. Subimal Datta, PhD, a professor in the University of Tennessee Health Science Center (UTHSC) Graduate School of… Read More


Professor Robert W. Williams Receives $300,000 Award from Research to Prevent Blindness To Fund Innovative Glaucoma Research

|

Glaucoma is a leading cause of irreversible blindness in the United States and globally. Currently, there is no cure for the disease, and once vision is lost, it cannot be regained. However, Robert. W. Williams, PhD, chair of the Department of Genetics, Genomics and Informatics at the University of Tennessee Health Science Center (UTHSC), has… Read More


Dr. Lawrence Pfeffer Publishes Findings on Gene that Inhibits Tumor Growth in Brain Cancer

|

Lawrence Pfeffer, PhD, Muirhead Professor of Pathology and director of the Center for Cancer Research at the University of Tennessee Health Science Center, is the principal author of a paper published in The Journal of Biological Chemistry that describes a little-known gene that could hold a key to future treatment of glioma, or brain cancer.… Read More


Associate Professor Mohamad Elabiad Receives $26,818 Grant for Blood Transfusion Research

|

Small amounts of two heavy metals, lead and mercury, are naturally present in human blood. In adult transfusions these amounts are not significant enough to cause any concern. For extremely premature infants, however, the story is different. Frequent blood transfusions, which naturally contain lead and mercury, theoretically increase the risk of toxicity from these metals… Read More