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Study determines mechanisms underlying abnormal development of nervous system in Hirschsprung disease

Written by Communications and Marketing

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Ankush Gosain, MD, PhD, of Le Bonheur Children’s Hospital and the University of Tennessee Health Science Center has focused his research on determining the mechanisms underlying abnormal development of the enteric nervous system in Hirschsprung disease. Gosain recently published a new study in The FASEB Journal delineating interactions between migrating neural crest cells and the extracellular matrix in a model of Hirschsprung disease using a variety of in vitro and in vivo approaches.

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