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Cellworks CBM Clinical Study Identifies Novel Biomarkers for ATRA Benefit and Failure in AML Patients


Cellworks Group, Inc., a world leader in Personalized Medicine in the key therapeutic areas of Oncology and Immunology, today announced results from a Cellworks Clinical Trial, in which the Cellworks Computational Omics Biology Model (CBM) accurately predicted that All-Trans Retinoic Acid (ATRA) combined with cytarabine, etoposide, idarubicin (ATRA-CEI) benefits a subset of non-APL (Acute Promyelocytic Leukemia) Acute Myeloid Leukemia (AML) patients. The study also revealed novel biomarkers and key mechanisms of resistance to ATRA-CEI benefit and failure in adults with AML. The results from this Cellworks clinical trial will be featured in a poster session with comments from Dr. Scott Howard, MD, MSc, University of Tennessee, Health Science Center, as part of the 2021 ASCO Annual Meeting June 4-8th during the Hematologic Malignancies-Leukemia, Myelodysplastic Syndromes, Allotransplant Track and available online as abstract 7027.

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