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An Immune Protein Could Prevent Severe COVID-19—if It Is Given at the Right Time

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The antiviral interferon might help early but exacerbate disease in later stages. “The interferon response is a little bit tricky,” says Rudragouda Channappanavar, a viral immunologist at the University of Tennessee Health Science Center, who was not involved with the new studies. The response protects the body from infections by thwarting viral replication. “The body needs it, without a doubt,” he says. “But viruses are smart. They have several proteins that can antagonize and suppress early interferon responses.”

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