The Department of Physiology Seminar Series continues TODAY, February 13th, with Dr. Abdul Majid, Postdoctoral Research Associate in the UTHSC Department of Physiology. His seminar titled “Calcium Modulation Attenuates Neuroinflammation in LPS-Stimulated Microglia” will be presented 3:30-5:00 PM in the Cancer Research Building Auditorium (19 S. Manassas St. Room 114). Refreshments will be provided.
Summary:
This study provides integrative insights into the essential role of calcium signaling in microglial activation within neuroinflammatory environments, a key component in the pathogenesis of neurological disorders. Attendees will gain an understanding of how calcium dynamics influence microglial behavior, particularly in the transition between pro-inflammatory and anti-inflammatory phenotypes, which is crucial for disease progression. The seminar will explore how calcium-modulating compounds (CMCs) can shift microglial states, reduce inflammatory cytokine release, and restore mitochondrial function disrupted by neuroinflammation. Through this comprehensive overview, participants will uncover novel therapeutic avenues targeting calcium signaling to mitigate neuroinflammatory responses and preserve neuronal health.
Brief Bio:
Dr. Abdul Majid is a Postdoctoral Research Associate in Dr. Djamel Lebeche’s lab at the University of Tennessee Health Science Center (UTHSC), specializing in biochemistry and molecular nutrition. He completed his Ph.D. at the University of Mysore, India, where his research focused on bioactive peptides for managing Type 2 diabetes and its complications. At UTHSC, his research explores the mechanisms of neuroinflammation, calcium signaling, and therapeutic strategies for diabetes and neurodegenerative diseases. He has received several accolades, including the Outstanding Postdoctoral Award at the UTHSC Research Showcase, and has secured independent research funding for his innovative work on calcium modulation in neuroinflammation. He actively contributes to academic service as an editor and reviewer for multiple scientific journals and is currently the president of the UTHSC Postdoc Association.