Publisher: News Medical Net


Collaborative project gets $20 million to develop new radiopharmaceutical cancer therapies

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UT Health Science Center researchers Gabor Tigyi, MD, PhD, Harriet Van Vleet Endowment Professor in Basic Oncology Research, Junming Yue, PhD, associate professor in the Department of Pathology, Sue Chin Lee, PhD, in the Department of Physiology, and David Schwartz, MD, chair of the Department of Radiation Oncology, are part of a scientific leadership group… Read More


Simple biomarkers offer early warning of hidden heart risk in childhood cancer survivors

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Data from the St. Jude lifetime cohort study (St. Jude LIFE) revealed that two common biomarkers of cardiac function and damage could better predict cardiomyopathy within five years than routine clinical evaluations in high-risk, asymptomatic childhood cancer survivors. Early detection through screening using these two biomarkers may lead to earlier treatment to prevent and protect against further… Read More


Newly designed molecule disrupts the infection mechanism of SARS-CoV-2

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A team of scientists led by the Department of Energy’s Oak Ridge National Laboratory designed a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and other viral diseases.


Scientists create new tool to identify genomic safe harbor sites in specific tissues

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Scientists at St. Jude Children’s Research Hospital have created a tool that can find safe places to introduce genes into human DNA. The tool is an early step in the process to improve the safety and efficacy of gene and cell therapies. The work appears today in Genome Biology. The study’s first authors are Dewan Shrestha, of St.… Read More


UTHSC receives $3.2 million to upgrade the Regional Biocontainment Laboratory

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The University of Tennessee Health Science Center has been awarded $3.2 million from the National Institute of Allergy and Infectious Diseases (NIAID) to upgrade the equipment and infrastructure in the UTHSC Regional Biocontainment Laboratory (RBL) on the Memphis campus to enhance the university’s research of infectious diseases, including COVID-19.


Study determines mechanisms underlying abnormal development of nervous system in Hirschsprung disease

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Ankush Gosain, MD, PhD, of Le Bonheur Children’s Hospital and the University of Tennessee Health Science Center has focused his research on determining the mechanisms underlying abnormal development of the enteric nervous system in Hirschsprung disease. Gosain recently published a new study in The FASEB Journal delineating interactions between migrating neural crest cells and the… Read More


Towbin receives NIH grant to study modifier genes in cardiomyopathy

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Jeffrey A. Towbin, MD, of Le Bonheur Children’s Hospital and the University of Tennessee Health Science Center was awarded a Research Project Grant (R01) from the National Institutes of Health (NIH) with co-principal investigators Enkhsaikha Purevjav, MD, PhD and Lu Lu, MD, MS. He is lead principal investigator on the project “Discovery of Modifier Genes… Read More


Kerafast offers the Delta-G-VSV Pseudotyping System for coronavirus research

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Kerafast Inc., developers of an online platform to facilitate access to unique lab-made bioresearch materials, today announced the availability of the Delta-G-VSV Pseudotyping System for coronavirus research applications. The system, developed by the Michael Whitt laboratory at the University of Tennessee, enables studies of SARS-CoV-2 viral entry and COVID-19 vaccine effectiveness at just biosafety level… Read More